Vendaje OPTIC™

A dehydrated extracellular amniotic allograft membrane for use as a scaffold for ocular repair

Vendaje OPTIC™ is a dehydrated, extracellular membrane allograft for use as a scaffold for ocular repair. The allograft is derived from human placental tissue, preserved to maintain the structural properties of the biologically active elements present in tissue regeneration.

Vendaje OPTIC™ is made up of three layers: epithelium, basement membrane, and stroma. Several types of collagen make up the basement membrane, including type VII collagen, which is also present in the conjunctival and corneal basement membranes. The stroma of Vendaje Optic™ can be subdivided further into a compact layer, a fibroblast layer, and an outer spongy layer.

Key Points

  • Single amniotic membrane layer

  • Contains full spectrum of growth factors

  • 150 microns in thickness

  • Bioscaffold containing extracellular matrix

  • High tensile strength

  • Anti-fibrotic and anti-adhesion barrier

  • Moderate levels of fibronectin and laminin5

  • No immune rejection2-4

Vendaje OPTIC™ is available in 8mm, 10mm and 12mm sizes.
1. Jingbo Liu, Hosam Sheha, Yao Fu, Lingyi Liang & Scheffer CG Tseng (2010) Update on amniotic membrane transplantation, Expert Review of Ophthalmology, 5:5, 645-661, DOI: 10.1586/eop.10.63

The immunology of successful pregnancy. Veenstra van Nieuwenhoven AL, Heineman MJ, Faas MM. Hum Reprod Update. 2003;9:347–357.

Immunogenicity of human amniotic membrane in experimental xenotransplantation. Kubo M, Sonoda Y, Muramatsu R, Usui M. Invest Ophthalmol Vis Sci. 2001;42:1539–1546.

Immunological characteristics of amniotic epithelium. Hori J, Wang M, Kamiya K, Takahashi H, Sakuragawa N. Cornea. 2006;25:0–58.

5 Olczyk P, Mencner Ł, Komosinska-Vassev K. The role of the extracellular matrix components in cutaneous wound healing. Biomed Res Int. 2014;2014:747584. doi:10.1155/2014/747584

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